Tomás Sobrino

Tomás Sobrino Principal Investigator

Dr. Tomás Sobrino has completed his PhD (Biochemistry and Molecular Biology, obtaining Extraordinary PhD Award) from the University of Santiago de Compostela. Currently he works as Miguel Servet Researcher, the highest professional category in Biomedical Research in Spain, in the Health Research Institute of Santiago de Compostela (IDIS). Likewise, he is assistant lecturer at the Medicine Department of University of Santiago de Compostela.

Dr. Tomás Sobrino was the first researcher who participated in the establishment of the Clinical Neurosciences Research Laboratory and the Unit of Cell Therapy and Neurorepair of the Health Research Institute of Santiago (IDIS). Dr. Sobrino leads all research lines of Neurorepair and Cell Therapy, but in turn he is also coordinate the teragnostic research focused on Alzheimer Disease. Moreover he participates in established lines of research: Hyperthermia and neuronal damage, excitotoxicitiy and neuronal damage, mechanisms of damage in stroke, diagnostic markers of stroke etiology, molecular markers of progression stroke, Inflammation and  metalloproteinases in brain ischemia, molecular uncoupling in acute brain ischemia, and molecular imaging and theranostics in stroke. This fact provides him the ability to conduct multidisciplinary research projects with clear translation to the clinic.

He has published more than 105 articles in indixed international scientific during the last 10 years. His research career is also been devoted to teach young professionals as researchers. Thus, he is the director of several undergraduate dissertations and PhD theses. He is also an editorial board member of 5 international scientific journals and a board member of several research consortia, highlighting the coordination of H2020 PANA project (


The Organization

The Servicio Galego de Saude (SERGAS) is an autonomous administrative body responsible for the management and provision of health services in the Public National Health Care system in the Region of Galicia (Population: 2.772.533). It includes a network of 14 hospitals, 3 of them university hospitals, 457 primary health care centers and more than 37.000 workers (7314 physicians). Biomedical research and development is one of the most important activities in the SERGAS.

The Health Research Institute of Santiago de Compostela (IDIS) of SERGAS is a center of research and innovation and knowledge transfer with a distinctly translational approach. The IDIS is composed by the synergies of two institutions, University of Santiago de Compostela and University Clinical Hospital of Santiago de Compostela (CHUS). [650] People are part of [63] research groups organized into six areas of Knowledge (Oncology [11 groups], Genetics and System Biology [13], endocrinology [15], neuroscience [10], Epidemiology [4] and inflammation [10]) and an area of support (technical and secretariat support platforms).
The Ramón Domínguez Foundation is the promoter of the IDIS and is co-participated by the Servizo Galego de Saude (Galician Health System, SERGAS) and the University of Santiago de Compostela (USC).
The Institute has published over 500 indexed original scientific articles per year. The annual budget managed by IDIS is about 15-18 million € raised in competitive calls for research projects, the recruitment of staff, agreements, contracts and provision of services, donations, and clinical trials. Around 100 international clinical trials are signed per year, and presented a portfolio of over 30 patents, 6 of them licensed.

Clinical Neurosciences Research Group develops research lines involved in the knowledge of nervous system diseases, with a special focus on acute cerebrovascular diseases and Alzheimer Disease. Its research aim is focused on the search for therapeutic and diagnostic targets in neurological disorders through a research clearly translational. Globally, its scientific production exceeds 1000 points of accumulated impact factor in the last 10 years. The median impact factor is approximately 5 points per paper. The research activity of the group is reflected not only in scientific papers, but we also teaching activities reflected in the direction of doctoral theses. At present our research is an excellence at the University of Santiago de Compostela and we coordinate the Spanish Network, from Instituto de Salud Carlos III (ISCIII). The funds managed by the Group of Clinical Neurosciences exceed € 10 million in the last eight years. Funding sources are both public (Instituto de Salud Carlos III, Ministry of Science and Innovation, Government of Galicia) and private (internationally multicenter clinical trials in phases II and III, research foundations, contracts with pharmaceutical companies: Bristol Myers Sqquib, Bayer, Uriach and Ferrer Internacional).

People Involved

Tomás Sobrino Position Head of Clinical Neurosciences Research Laboratory Role in PANA Coordinator
José Castillo Position Head of Neurology Department Role in PANA Senior investigator
Francisco Campos Position Researcher/PhD Role in PANA Senior researcher
José Manuel Aldrey Position Neurologist/MD Role in PANA Neurologist
Juan Pías Position Neurologist/MD Role in PANA Neurologist
Natalia Nieto Position Nurse. Neurology department Role in PANA Nurse
Juan Pardo Position Researcher/PhD Role in PANA Senior researcher
Pablo Aguiar Fernández Position Researcher/PhD Role in PANA Senior researcher
Ramón Iglesias Position PhD Researcher. MRI Unit Manager. Role in PANA MRI imaging and imaging analysis
Juan Doval Position PhD. Researcher in Neuroimaging Role in PANA MRI imaging and imaging analysis
Teresa Oreiro García Position Project Manager. PharmD. PhD. Role in PANA Project Manager
This project has received funding from the European Union´s Horizon 2020 research and innovation programme under grant agreement No 686009


Clinical Neuroscience Research Laboratory
University Clinical Hospital Santiago
A Building, -4 Floor
E15706 A Coruña, Spain
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